Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482161 | 1.00 | CYP19A1 (0.48) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL11327393 | 1.00 | CYP19A1 (0.48) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL11774237 | 0.87 | CYP19A1 (0.46) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL11156713 | 0.86 | CYP19A1 (0.51) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL19625947 | 0.86 | CYP19A1 (0.51) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL29076625 | 0.85 | CYP19A1 (0.44) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL144721 | 0.83 | GRIN1 (0.55) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL29875956 | 0.83 | GRIN1 (0.55) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL20677083 | 0.83 | GRIN1 (0.55) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 | |
| SCHEMBL350132 | 0.83 | GRIN1 (0.55) | CYP19A1GPBAR1LMNAEPHA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002483-A1 | Use of ester and ether derivatives of 4-hydroxy-19-norandrosterone to increase the level of the anabolic/androgenic hormone 4-hydroxy-19-nortestosterone in humans | Paternoster, Mr. Vince | 2004-01-01 | — | — | US | disclosed |
| US-20030199487-A1 | Ester and ether derivatives of 4-hydroxytestosterone and a method for the regulation of athletic function in humans | Paternoster, Mr. Vince | 2003-10-23 | — | — | US | disclosed |
| US-20030199486-A1 | Ester and ether derivatives of 4-hydroxy-19-nortestosterone and a method for the regulation of athletic function in humans | NUTRI SPORT PHARMACAL, INC. (US) | 2003-10-23 | — | — | US | disclosed |
| US-4301246-A | HYDROXYLATION OF 3-KETO-BISNORCHOLENOL TO 7-HYDROXY-3-KETO-BISNORCHOLENOL | HOFFMANN-LA ROCHE INC. (US) | 1981-11-17 | — | — | US | disclosed |
| US-4230625-A | DISSOLVING GALLSTONES | HOFFMANN-LA ROCHE INC. (US) | 1980-10-28 | — | — | US | disclosed |