Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925581 | 1.00 | OGA (0.34) | OGAITGB3ITGA2BPSEN1PSEN2 | |
| SCHEMBL6925602 | 1.00 | OGA (0.34) | OGAITGB3ITGA2BPSEN1PSEN2 | |
| SCHEMBL6926536 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6926533 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6926539 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6923365 | 0.79 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6923375 | 0.79 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6924333 | 0.79 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6923371 | 0.79 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6924328 | 0.79 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518299-B1 | Trans-5-(1-Acetylamino-2-ethyl)butyl-1 -aminoiminomethylpyrrolidine-3-carboxylic acid | BIOCRYST PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |