Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866501 | 0.92 | SIGMAR1 (0.58) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL30418043 | 0.88 | SIGMAR1 (0.66) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL30418669 | 0.86 | SIGMAR1 (0.68) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL17107153 | 0.85 | BCHE (0.49) | SIGMAR1CYP1A2CYP2A6MC4RMC5R | |
| SCHEMBL30746339 | 0.82 | SIGMAR1 (0.68) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL5221573 | 0.81 | SIGMAR1 (0.54) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL1127649 | 0.81 | CYP1A2 (0.54) | SIGMAR1HDAC1HDAC8CYP1A2NAAA | |
| SCHEMBL3941594 | 0.80 | CYP1A2 (0.65) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL1610472 | 0.79 | SIGMAR1 (0.56) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL11515396 | 0.79 | SIGMAR1 (0.61) | SIGMAR1HDAC1HDAC8CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846681-B1 | NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD | NIPPON SODA CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6093753-A | CURABLE COMPOSITION COMPRISING A CATIONIC POLYMERIZABLE COMPOUND WHICH IS AN ALICYCLIC EPOXY COMPOUND OR A VINYL ETHER COMPOUND AND A CATIONIC POLYMERIZATION INITIATOR; PAINTS, ADHESIVES, INKS, PHOTORESISTS | NIPPON SODA CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0846681-A1 | NOVEL SULFONIUM SALT COMPOUNDS, POLYMERIZATION INITIATOR, CURABLE COMPOSITION, AND CURING METHOD | NIPPON SODA CO., LTD. (JP) | 1998-06-10 | — | — | EP | disclosed |