Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 12/20 | 0.51 |
| ▸ | CA9 | Q16790 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438140 | 0.84 | LMNA (0.60) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL15092710 | 0.84 | LMNA (0.60) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL28586686 | 0.84 | LMNA (0.47) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL8373971 | 0.83 | LMNA (0.67) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL28597167 | 0.83 | LMNA (0.46) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL21465946 | 0.80 | LMNA (0.56) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL18798676 | 0.80 | LMNA (0.68) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL12630504 | 0.80 | LMNA (0.59) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| Dipyridyl SCHEMBL28477054 | 0.80 | LMNA (0.44) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL827876 | 0.79 | LMNA (0.58) | LMNAKMT2AKDM4ECYP1A2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082284-B | Artemisia dobesilate H derivative, pharmaceutical composition thereof, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-11-17 | — | — | CN | claimed |
| CN-116082284-A | Artemisia dobesilate H derivative, pharmaceutical composition thereof, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-05-09 | — | — | CN | claimed |
| CN-112110987-B | 5-fluorouracil modified by asparaginyl theanine and phenylalanine, synthesis, activity and application thereof | 首都医科大学 | 2023-05-05 | — | — | CN | claimed |
| CN-112300245-B | RGDS and theanine co-modified 5-fluorouracil, and synthesis, activity and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-112300244-B | 5-fluorouracil modified by theanine alone or together with RGDS, and synthesis, activity and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-112300246-B | 5-fluorouracil modified by aspartyl theanine RGDS, and synthesis, activity and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115304691-A | Inclusion and application of 5-fluorouracil modified cyclodextrin derivative and berberine | 首都医科大学 | 2022-11-08 | — | — | CN | claimed |
| CN-112390854-B | 5-fluorouracil modified by theanine and RGDS together, and synthesis, activity and application thereof | 首都医科大学 | 2022-10-21 | — | — | CN | claimed |
| CN-113105483-B | Tricyclohexylphosphine 5-fluorouracil-1-yl acetic acid mononuclear silver complex and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2022-09-06 | — | — | CN | claimed |
| CN-112010811-B | 5-fluorouracil modified by theanine and phenylalanine together, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | claimed |
| CN-109369625-B | Ortho ester 5-fluorouracil prodrug molecule, preparation method thereof, acid-sensitive nanoparticle thereof and application | 安徽大学 | 2020-08-04 | — | — | CN | claimed |
| CN-107459552-B | carbolinoyl-AA-fluorouracil acetyl-Orn-NHCH2C6H5Their synthesis, activity and use | 首都医科大学 | 2020-03-17 | — | — | CN | claimed |
| CN-107459550-B | Carboline formyl-AA-fluorouracil-acetyl-Orn-NHCH2C6H5Their synthesis, activity and use | 首都医科大学 | 2020-03-17 | — | — | CN | claimed |
| US-10086010-B2 | Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells | STC.UNM (US) | 2018-10-02 | — | — | US | claimed |
| US-20180125875-A1 | SYNERGISTIC ENHANCEMENT OF 5-FLUOROURACIL CYTOTOXICITY BY DEOXYURIDINE ANALOGS IN CANCER CELLS | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2018-05-10 | — | — | US | claimed |
| WO-2015142867-A1 | SYNERGISTIC ENHANCEMENT OF 5-FLUOROURACIL CYTOTOXICITY BY DEOXYURIDINE ANALOGS IN CANCER CELLS | STC.UNM (US) | 2015-09-24 | — | — | WO | claimed |
| CN-101485887-B | 5-fluorouracil-sn2-phosphatidyl choline copolymer and preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2011-06-29 | — | — | CN | claimed |
| CN-101485887-A | 5-fluorouracil-sn2-phosphatidyl choline copolymer as well as preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2009-07-22 | — | — | CN | claimed |
| CN-101417144-A | Eye medicine-loaded implantation film and preparation method thereof | BEIJING TONGREN HOSPITAL CAPIT (CN) | 2009-04-29 | — | — | CN | claimed |
| WO-2005116058-A1 | PEPTIDES USEFUL FOR TREATING GNRH ASSOCIATED DISEASES | CUREPEPTIDE LTD. (IL) | 2005-12-08 | — | — | WO | claimed |