Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926872 | 0.83 | NPY5R (0.43) | NPY5RACHEBCHEHRH1HRH2 | |
| SCHEMBL31037658 | 0.81 | KDM4E (0.45) | ADORA2AGBA1 | |
| SCHEMBL1456869 | 0.75 | KDM4E (0.52) | ACHEBCHEEGFRALDH1A1MAPT | |
| SCHEMBL12744387 | 0.75 | POLB (0.58) | EGFRALDH1A1MAPTHRH1CHRM2 | |
| SCHEMBL12744367 | 0.75 | EGFR (0.47) | EGFRALDH1A1MAPTHRH1CHRM2 | |
| SCHEMBL14850955 | 0.74 | SLC2A1 (0.55) | ACHEBCHEALDH1A1HRH3ADRA2B | |
| SCHEMBL3961147 | 0.74 | MAPT (0.57) | ACHEBCHEEGFRALDH1A1MAPT | |
| SCHEMBL14842148 | 0.73 | KMT2A (0.57) | ACHEBCHEALDH1A1MAPTHRH3 | |
| SCHEMBL203833 | 0.73 | POLB (0.60) | ACHEBCHEEGFRALDH1A1MAPT | |
| SCHEMBL6723473 | 0.73 | KDM4E (0.51) | EGFRALDH1A1MAPTHRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| CN-1323307-A | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |