Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926323 | 0.83 | NPY5R (0.39) | NPY5RACHEBCHEHRH3HRH2 | |
| SCHEMBL6923708 | 0.78 | KDM4E (0.48) | NPY5RKDM4EKMT2A | |
| SCHEMBL12744366 | 0.72 | APP (0.55) | ACHEBCHESLC2A1KDM4ENPC1 | |
| SCHEMBL21755868 | 0.70 | KMT2A (0.63) | ACHEBCHEHRH3SLC2A1KDM4E | |
| SCHEMBL6926471 | 0.70 | ACHE (0.45) | ACHEHRH2LMNAPOLBNPSR1 | |
| SCHEMBL213949 | 0.70 | KCNH3 (0.46) | NPY5RACHEKDM4ENPC1LMNA | |
| SCHEMBL202694 | 0.70 | POLB (0.68) | ACHEBCHESLC2A1KDM4ENPC1 | |
| SCHEMBL22181050 | 0.70 | ACHE (0.55) | ACHEBCHESLC2A1NPC1POLB | |
| SCHEMBL6719555 | 0.70 | KDM4E (0.57) | SLC2A1KDM4ENPC1LMNAGLA | |
| SCHEMBL6838638 | 0.69 | NPY5R (0.42) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| CN-1323307-A | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |