SCHEMBL69265

SCHEMBL69265

Cc1cc(O)c(C(C)C)cc1Cc1cc(C(C)C)c(O)cc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
CYP2D6 P10635 3/20 0.58
MAPK1 P28482 1/20 0.58
LMNA P02545 5/20 0.57
PKM P14618 3/20 0.47
TRPV1 Q8NER1 3/20 0.46
TRPA1 O75762 1/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
MAPT P10636 5/20 0.41
KMT2A Q03164 3/20 0.41
THRB P10828 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
ALOX15 P16050 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
ALDH1A1 P00352 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252526 0.86 CYP1A2 (0.57) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL1245168 0.86 CYP1A2 (0.57) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL28228079 0.82 CYP1A2 (0.54) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL6235501 0.82 TRPV1 (0.56) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL214157 0.80 LMNA (0.68) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL29872559 0.80 LMNA (0.68) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL6661840 0.80 TRPV1 (0.60) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL6229373 0.80 CYP1A2 (0.51) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL9556365 0.78 LMNA (0.65) CYP1A2CYP2D6MAPK1LMNAPKM
SCHEMBL1245089 0.78 LMNA (0.65) CYP1A2CYP2D6MAPK1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0333445-B1 Aromatic allene compounds and preparation thereof NIPPON PAINT CO LTD (JP) 1995-01-18 EP disclosed
US-5340931-A Chemical intermediates for allyl or vinyl ether polymers NIPPON PAINT CO., LTD. (JP) 1994-08-23 US disclosed
EP-0457334-B1 Carbonates of acetylenic alcohols NIPPON PAINT CO LTD (JP) 1994-08-10 EP disclosed
US-5258542-A Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1993-11-02 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
US-4374959-A Block copolymers of polyphenylene oxides and non-sterically-hindered high molecular weight aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1983-02-22 US disclosed
US-4374233-A MOLDING MATERIALS; ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1983-02-15 US disclosed
US-4368315-A AGITATED TWO-PHASE MIXTURE OF ORGANIC SOLVENT AND WATER CONTAINING STRONG BASE GENERAL ELECTRIC COMPANY (US) 1983-01-11 US disclosed
US-4360659-A Non-catalyzed interfacial polycondensation polycarbonate process GENERAL ELECTRIC COMPANY (US) 1982-11-23 US disclosed
US-4345050-A Block copolymers of polyphenylene oxides and polyformals on non-sterically-hindered dihydric phenols GENERAL ELECTRIC COMPANY (US) 1982-08-17 US disclosed
US-4281088-A Novel halobisphenolethylene polycarbonate-polyester blends GENERAL ELECTRIC COMPANY (US) 1981-07-28 US disclosed
US-4247662-A Novel halobisphenolethylene polycarbonate-vinyl aromatic resin blends GENERAL ELECTRIC COMPANY (US) 1981-01-27 US disclosed
US-4225687-A MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1980-09-30 US disclosed
US-4217438-A Polycarbonate transesterification process GENERAL ELECTRIC COMPANY (US) 1980-08-12 US disclosed
US-4118370-A ESTERIFIED HINDERED PHENOL; MOLDING MATERIALS, FIBERS, LAMINATES GENERAL ELECTRIC COMPANY (US) 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP1A2 2262/4885CYP2D6 3747/4885MAPK1 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.