Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030673 | 0.90 | CSNK2B (0.47) | CSNK2A2CSNK2BCSNK2A1MAPTRXFP1 | |
| SCHEMBL2031070 | 0.84 | CSNK2B (0.40) | CSNK2A2CSNK2BCSNK2A1MAPTRXFP1 | |
| SCHEMBL2031069 | 0.84 | CSNK2B (0.40) | CSNK2A2CSNK2BCSNK2A1MAPTRXFP1 | |
| SCHEMBL6927674 | 0.84 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL12644562 | 0.81 | CSNK2B (0.47) | CSNK2A2CSNK2BCSNK2A1MAPTNPC1 | |
| SCHEMBL2030917 | 0.77 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1EGFRCDK2 | |
| SCHEMBL2030915 | 0.77 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1EGFRCDK2 | |
| SCHEMBL12583803 | 0.75 | CSNK2B (0.39) | CSNK2BMAPTRXFP1TP53POLB | |
| SCHEMBL17641222 | 0.75 | CSNK2B (0.39) | CSNK2BMAPTRXFP1TP53POLB | |
| SCHEMBL1934230 | 0.75 | CSNK2B (0.63) | CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068667-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |