Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 15/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926567 | 0.84 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2028616 | 0.81 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1PAK4 | |
| SCHEMBL6926560 | 0.81 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1PAK4 | |
| SCHEMBL2028622 | 0.81 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1PAK4 | |
| SCHEMBL1934230 | 0.81 | CSNK2B (0.63) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL19526864 | 0.79 | CSNK2B (0.50) | CSNK2A2CSNK2BCSNK2A1PAK4 | |
| SCHEMBL12645330 | 0.78 | CSNK2B (0.66) | CSNK2A2CSNK2BCSNK2A1KCNH2 | |
| SCHEMBL17641217 | 0.76 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2028352 | 0.76 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL12583816 | 0.76 | CSNK2B (0.46) | CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068667-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |