SCHEMBL692672

SCHEMBL692672

CC(=O)[Si](C)(CC(C)C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14760202 0.70 ALDH1A1 (0.41) ALDH1A1TDP1
SCHEMBL14760075 0.66 TSHR (0.33) ALDH1A1TDP1
SCHEMBL622918 0.64 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL476108 0.63 TSHR (0.35) ALDH1A1TDP1
SCHEMBL7924035 0.63 TSHR (0.35) ALDH1A1TDP1
SCHEMBL17735525 0.62
SCHEMBL475931 0.60 TSHR (0.36) ALDH1A1TDP1
SCHEMBL6054113 0.60 TSHR (0.36) ALDH1A1TDP1
SCHEMBL2149328 0.60 TSHR (0.36) ALDH1A1TDP1PIK3CD
SCHEMBL9247216 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421873-B1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2014-07-02 EP disclosed
EP-2421873-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL Givaudan SA (CH) 2012-02-29 EP disclosed
WO-2010121979-A1 ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL GIVAUDAN SA (CH) 2010-10-28 WO disclosed