Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.52 |
| ▸ | SRC | P12931 | 5/20 | 0.52 |
| ▸ | PRKDC | P78527 | 4/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | HCK | P08631 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | ATG7 | O95352 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10261070 | 0.83 | SRC (0.52) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL27943325 | 0.82 | PIK3CD (0.40) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL14647490 | 0.80 | PIK3CD (0.47) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL868521 | 0.79 | DYRK3 (0.51) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL19476278 | 0.79 | ADORA2A (0.49) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL6929476 | 0.78 | PIK3CD (0.48) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL29780889 | 0.73 | SRC (0.64) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL12758 | 0.72 | ADORA2A (0.46) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL29052149 | 0.70 | ADORA2A (0.49) | PIK3CDSRCPRKDCPIK3CGPIK3CB | |
| SCHEMBL29781034 | 0.70 | ADORA2A (0.49) | PIK3CDSRCPRKDCPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119663-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |