Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28418543 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EMAPTATM | |
| SCHEMBL13332956 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EMAPTATM | |
| SCHEMBL383436 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EMAPTATM | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL5661 | 1.00 | — | — | |
| SCHEMBL9797557 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EMAPTATM | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL29193681 | 0.96 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL11534774 | 0.96 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL435434 | 0.96 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL3965529 | 0.96 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL4079465 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211240-A4 | BISCYCLOPROPANECARBOXYLIC ACID AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | AJINOMOTO KK (JP) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001016091-A1 | BISCYCLOPROPANECARBOXYLIC ACID AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | AJINOMOTO CO.,INC. (JP) | 2001-03-08 | — | — | WO | disclosed |