SCHEMBL383436

SCHEMBL383436

NC(=O)C1CCC(C(N)=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
CYP2D6 P10635 1/20 0.46
NOS2 P35228 1/20 0.44
GAA P10253 1/20 0.43
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
PLG P00747 1/20 0.38
PLAT P00750 1/20 0.38
CYP3A4 P08684 1/20 0.38
EPHX1 P07099 1/20 0.38
MEN1 O00255 1/20 0.38
APEX1 P27695 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.36
OR51E2 Q9H255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28418543 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KMT2AKDM4EMAPTATM
SCHEMBL13332956 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KMT2AKDM4EMAPTATM
Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KMT2AKDM4EMAPTATM
Cyclopropanecarboxylic Acid Amide SCHEMBL5661 1.00
SCHEMBL9797557 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KMT2AKDM4EMAPTATM
Cyclopropanecarboxylic Acid Amide SCHEMBL29193681 0.96
Cyclopropanecarboxylic Acid Amide SCHEMBL11534774 0.96
Cyclopropanecarboxylic Acid Amide SCHEMBL435434 0.96
Cyclopropanecarboxylic Acid Amide SCHEMBL3965529 0.96
Cyclopropanecarboxylic Acid Amide SCHEMBL4079465 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117899762-A Fluidized bed reaction device and method for preparing nitrile compounds 上海巽田科技股份有限公司 2024-04-19 CN claimed
US-4203916-A Preparation of trans cyclohexane 1,4 diisocyanate AKZONA INCORPORATED (US) 1980-05-20 US claimed
EP-3778544-B1 PRODUCTION METHOD FOR 1,4-CYCLOHEXANEDICARBOXYLIC ACID DERIVATIVE, 1,4-DICYANOCYCLOHEXANE AND 1,4-BIS(AMINOMETHYL)CYCLOHEXANE MITSUBISHI GAS CHEMICAL CO (JP) 2026-05-20 EP disclosed
US-20260103582-A1 PRODUCTION METHOD FOR GLASS FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION GLOBAL POLYACETAL CO., LTD. (JP) 2026-04-16 US disclosed
US-12534597-B2 Polyamide resin composition and molded object thereof KURARAY CO., LTD. (JP) 2026-01-27 US disclosed
US-12448515-B2 Method for producing polyamide resin composition TOYOBO MC CORPORATION (JP) 2025-10-21 US disclosed
EP-3992240-B1 POLYAMIDE RESIN COMPOSITION FOR FOAM MOLDING AND FOAM MOLDED BODY TOYOBO MC CORP (JP) 2025-08-06 EP disclosed
EP-4596201-A1 PRODUCTION METHOD FOR GLASS FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION GLOBAL POLYACETAL CO., LTD. (JP) 2025-08-06 EP disclosed
EP-4585641-A1 RESIN COMPOSITION FOR LASER MARKING TOYOBO MC Corporation (JP) 2025-07-16 EP disclosed
EP-3742033-B1 MULTILAYER TUBE UBE CORP (JP) 2025-06-11 EP disclosed
WO-2025094869-A1 POLYAMIDE RESIN COMPOSITION UBE株式会社 2025-05-08 WO disclosed
WO-1984001161-A1 LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO disclosed
WO-1984001160-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO disclosed
US-4439370-A Preparation of trans cyclohexane 1,4-diisocyanate AKZONA INCORPORATED (US) 1984-03-27 US disclosed
US-4418211-A Preparation of trans-cyclohexane-1,4-disulphonyl urea AKZONA INCORPORATED (US) 1983-11-29 US disclosed
US-4275223-A Preparation of trans-cyclohexane-1,4-diurethanes AKZONA INCORPORATED (US) 1981-06-23 US disclosed
US-4259258-A Preparation of bis-n-chloramides of cycloaliphatic carboxylic acids AKZONA INCORPORATED (US) 1981-03-31 US disclosed
US-4256558-A EXTRUSION OF A BLEND OF POLYETHYLENE TEREPHTHALATE AND A DIALLYL COMPOUND FOLLOWED BY RADIATION CURING; FILMS AND FILAMENTS HAVING GOOD HEAT RESISTANCE AND PHOTOSTABILITY TEIJIN LIMITED (JP) 1981-03-17 US disclosed
US-4203916-A Preparation of trans cyclohexane 1,4 diisocyanate AKZONA INCORPORATED (US) 1980-05-20 US disclosed
US-4053510-A REACTING A DICARBOXYLIC ACID WITH UREA IN CHLOROSULFONIC ACID OR OLEUM AKZO N.V. (NL) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534597-B2 Polyamide resin composition and molded object thereof SMC2, DAP3, RPTOR SMN1; SMN2 2453/4885KMT2A 1013/4885KDM4E 1860/4885
US-20260103582-A1 PRODUCTION METHOD FOR GLASS FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION PGA5, TNF, VMA21 SMN1; SMN2 542/4885KMT2A 1171/4885KDM4E 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.