Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926130 | 0.90 | GRM5 (0.65) | GRM5 | |
| SCHEMBL6926128 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL6925776 | 0.87 | GRM5 (1.00) | GRM5 | |
| SCHEMBL6926154 | 0.85 | GRM5 (0.77) | GRM5 | |
| SCHEMBL6926199 | 0.85 | GRM5 (0.58) | GRM5 | |
| SCHEMBL6927340 | 0.85 | GRM5 (0.76) | GRM5 | |
| SCHEMBL12416366 | 0.85 | GRM5 (0.76) | GRM5P2RY14 | |
| SCHEMBL6925820 | 0.82 | GRM5 (0.76) | GRM5 | |
| SCHEMBL6926086 | 0.80 | GRM5 (1.00) | GRM5 | |
| SCHEMBL6927146 | 0.79 | GRM5 (0.80) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035174-A1 | SUBSTITUTED HETEROARYLAMINE CARBOXAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | VANDERBILT UNIVERSITY (US) | 2011-03-24 | — | — | WO | disclosed |