⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178388 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1578109 | 0.97 | POLB (0.48) | — | |
| Hydrochloric Acid SCHEMBL1318698 | 0.97 | POLB (0.48) | — | |
| Bromide SCHEMBL452246 | 0.97 | POLB (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL238025 | 0.97 | POLB (0.48) | — | |
| SCHEMBL3971660 | 0.97 | CXCR4 (0.52) | — | |
| Methylamine SCHEMBL928302 | 0.95 | POLB (0.46) | — | |
| Bromide SCHEMBL11717124 | 0.95 | POLB (0.46) | — | |
| Hydrochloric Acid SCHEMBL28781885 | 0.95 | POLB (0.46) | — | |
| Dimethylamine SCHEMBL4062959 | 0.93 | POLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355635-B1 | IMIDAZOLEBENZENE, IMIDAZOLEPYRIDINE COMPOUNDS FOR TREATMENT OF OBESITY | PFIZER INC. | 2002-03-12 | — | — | US | claimed |
| US-20010039277-A1 | Compounds for the treatment of obesity | ELLIOTT RICHARD L (US) | 2001-11-08 | — | — | US | claimed |
| WO-2000066578-A1 | COMPOUNDS FOR THE TREATMENT OF OBESITY | PFIZER PRODUCTS INC. (US) | 2000-11-09 | — | — | WO | claimed |
| EP-1020447-A1 | PYRAZOLE COMPOUNDS AND PLANT DISEASE CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2000-07-19 | — | — | EP | claimed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | claimed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | claimed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | claimed |
| US-9150545-B2 | Carboxamide compounds and their use as calpain inhibitors V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20150065477-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-03-05 | — | — | US | disclosed |
| US-6514966-B2 | Neuropeptide Y antagonists such as 2-chloro-5-(4-(3,4-dich loro-phenyl)-1H-imidazol-2-yl)-pyridine | PFIZER INC. | 2003-02-04 | — | — | US | disclosed |
| US-6355635-B1 | IMIDAZOLEBENZENE, IMIDAZOLEPYRIDINE COMPOUNDS FOR TREATMENT OF OBESITY | PFIZER INC. | 2002-03-12 | — | — | US | disclosed |
| US-20010039277-A1 | Compounds for the treatment of obesity | ELLIOTT RICHARD L (US) | 2001-11-08 | — | — | US | disclosed |
| WO-2000066578-A1 | COMPOUNDS FOR THE TREATMENT OF OBESITY | PFIZER PRODUCTS INC. (US) | 2000-11-09 | — | — | WO | disclosed |
| US-5387686-A | Sublimable, yellow quinoline derivatives; storage stable; heat light, chemical resistant | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5296445-A | Quinoline dyes | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0527051-A1 | Quinophthalone dyes, ink composition and transfer sheet containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | disclosed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | disclosed |
| US-4034094-A | 8-Alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acids for treating urinary tract infections | LABORATOIRE ROGER BELLOW (FR) | 1977-07-05 | — | — | US | disclosed |