Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314882 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1CA1CA2MAOA | |
| SCHEMBL6315978 | 0.85 | PTGS2 (0.40) | PTGS2PTGS1CA1CA2ALDH1A1 | |
| SCHEMBL6307672 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1CA1CA2MAOA | |
| SCHEMBL6310924 | 0.77 | PTGS2 (0.42) | PTGS2PTGS1CA1CA2ALDH1A1 | |
| SCHEMBL6309703 | 0.77 | PTGS2 (0.45) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6314778 | 0.77 | PTGS2 (0.45) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL6314767 | 0.75 | PTGS2 (0.35) | PTGS2PTGS1CA1CA2MEN1 | |
| SCHEMBL6309064 | 0.75 | PTGS1 (0.37) | PTGS2PTGS1CA1CA2MAOA | |
| SCHEMBL6314088 | 0.75 | PTGS2 (0.46) | PTGS2PTGS1CA1CA2MAOA | |
| SCHEMBL6315835 | 0.74 | PTGS2 (0.49) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515014-B2 | Aminosulfonyl- or alkylsulfonylphenyl-heterocyclylalkylhydroxyamic acid or hydroxyurea derivatives; treating asthma and arthritis | G. D. SEARLE & CO. | 2003-02-04 | — | — | US | disclosed |