SCHEMBL69276

SCHEMBL69276

CCOC(=O)/C=C/c1ccc(Br)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.73
CA1 P00915 1/20 0.73
CA2 P00918 1/20 0.73
CA7 P43166 1/20 0.73
CA9 Q16790 1/20 0.73
CA14 Q9ULX7 1/20 0.73
CYP3A4 P08684 1/20 0.63
LMNA P02545 3/20 0.62
NPSR1 Q6W5P4 2/20 0.62
ALDH1A1 P00352 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
TTR P02766 1/20 0.62
DPP4 P27487 1/20 0.62
MAPT P10636 3/20 0.57
MEN1 O00255 2/20 0.57
MAPK1 P28482 2/20 0.57
KMT2A Q03164 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13957564 1.00 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL69277 1.00 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL10460369 0.98 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL10460368 0.98 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL9060373 0.95 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL9060367 0.95 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL13957401 0.91 CA12 (0.86) CA12CA1CA2CA7CA9
SCHEMBL10939791 0.91 CA12 (0.86) CA12CA1CA2CA7CA9
SCHEMBL5059085 0.91 CA12 (0.86) CA12CA1CA2CA7CA9
SCHEMBL1260527 0.89 CA12 (0.83) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115594686-B Millpulin A derivative, preparation method and medical application thereof 沈阳药科大学 2023-10-13 CN claimed
CN-115594686-A Millpuline A derivatives, and preparation method and medical application thereof 沈阳药科大学(CN) 2023-01-13 CN claimed
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells NORTHEAST NORMAL UNIVERSITY (CN) 2020-07-28 US claimed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP claimed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US claimed
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS NORTHEAST NORMAL UNIVERSITY (CN) 2018-07-12 US claimed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US claimed
EP-3208301-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME Tosoh Corporation (JP) 2017-08-23 EP claimed
CN-106795327-A Resin composition and optical compensation film using the same 东曹株式会社 2017-05-31 CN claimed
CN-101774918-A Preparation method of cinnamate derivates UNIV HUAQIAO 2010-07-14 CN claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
EP-4567018-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-06-11 EP disclosed
CN-119241515-A Double-target inhibitor targeting LSD1 and EZH2 as well as preparation method and application thereof 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2025-01-03 CN disclosed
CN-118834490-A Photo-crosslinkable perfluorinated ion membrane and preparation method thereof 上海交通大学 2024-10-25 CN disclosed
WO-2024029525-A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND ダイキン工業株式会社 2024-02-08 WO disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
CN-1045576-A Pesticide WELLCOME FOUND (GB) 1990-09-26 CN disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed
US-4335054-A Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
US-4226878-A ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES KISSEI PHARMACEUTICAL CO., LTD. (JP) 1980-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS XPA, MEP1A, EED CA12 4873/4885CA1 4879/4885CA2 4877/4885
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells XPA, MEP1A, EED CA12 4873/4885CA1 4879/4885CA2 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.