Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388605 | 0.84 | CYP3A4 (0.43) | PTPN1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28673323 | 0.83 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL73063 | 0.82 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4678770 | 0.81 | PTPN1 (0.49) | PTPN1KIF11CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL9719820 | 0.81 | PTPN1 (0.49) | PTPN1KIF11CYP3A4CYP2D6SLC6A2 | |
| Bromomethane SCHEMBL209562 | 0.80 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL3674757 | 0.80 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28727492 | 0.80 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrogen Sulfide SCHEMBL28066375 | 0.80 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrogen Sulfide SCHEMBL27894390 | 0.80 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1104415-C | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI SEIYAKU CO (JP) | 2003-04-02 | — | — | CN | disclosed |
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| CN-1232449-A | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI SEIYAKU CO (JP) | 1999-10-20 | — | — | CN | disclosed |
| EP-0936215-A1 | PROCESS FOR PREPARING 2-PHENYL-3-NAPHTHYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | PROC, F12, F2 | PTPN1 2909/4885HDAC3 1872/4885HDAC4 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.