Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928048 | 1.00 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6928056 | 1.00 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL27810375 | 0.89 | TSHR (0.42) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL7436520 | 0.84 | TSHR (0.39) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL10991321 | 0.81 | TSHR (0.36) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6930982 | 0.80 | SMN1; SMN2 (0.38) | TSHRKDM4EALDH1A1MAPK1 | |
| SCHEMBL6930988 | 0.80 | SMN1; SMN2 (0.38) | TSHRKDM4EALDH1A1MAPK1 | |
| SCHEMBL19006444 | 0.80 | SMN1; SMN2 (0.38) | TSHRKDM4EALDH1A1MAPK1 | |
| SCHEMBL6930984 | 0.80 | SMN1; SMN2 (0.38) | TSHRKDM4EALDH1A1MAPK1 | |
| SCHEMBL11036366 | 0.79 | TSHR (0.34) | TSHRKDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586616-B1 | Cyanation and esterification of 3,4-epoxybutyric acid sodium salts to form chemical intermediates for antilipemic agents; by-product inhibition | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2003-07-01 | — | — | US | disclosed |
| EP-1149068-A4 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1149068-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | Samsung Fine Chemicals Co., Ltd. (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046186-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2000-08-10 | — | — | WO | disclosed |