Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991321 | 0.98 | TSHR (0.36) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL27810375 | 0.85 | TSHR (0.42) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL7436520 | 0.81 | TSHR (0.39) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6928056 | 0.79 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6928051 | 0.79 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6928048 | 0.79 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL2783538 | 0.73 | SMN1; SMN2 (0.41) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11442409 | 0.72 | TSHR (0.42) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL7775457 | 0.72 | TSHR (0.42) | TSHRKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL10991696 | 0.69 | TSHR (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59204187-A | — | — | None | — | — | JP | disclosed |
| JP-S59204187-A | DITHIOLANE DERIVATIVE, ITS USE AND ITS PREPARATION | NIPPON NOHYAKU CO LTD | 1984-11-19 | — | — | JP | disclosed |