Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167148 | 0.79 | AXL (0.41) | AXLNUDT1BRD4APPMAPK1 | |
| SCHEMBL6929283 | 0.79 | CCR1 (0.50) | CCR1AXLNUDT1BRD4APP | |
| SCHEMBL31283256 | 0.79 | AXL (0.41) | AXLNUDT1BRD4APPMAPK1 | |
| Hydrochloric Acid SCHEMBL4976930 | 0.78 | AXL (0.39) | AXLNUDT1BRD4APPCDK8 | |
| SCHEMBL12874655 | 0.77 | KCNH2 (0.43) | AXLNUDT1BRD4APPAHR | |
| SCHEMBL11888031 | 0.76 | AXL (0.38) | AXLNUDT1BRD4APPPIK3CD | |
| SCHEMBL12807007 | 0.76 | KCNH2 (0.50) | AXLNUDT1BRD4 | |
| SCHEMBL10130905 | 0.75 | AXL (0.37) | AXLNUDT1BRD4APPMAPK1 | |
| SCHEMBL5925823 | 0.75 | AXL (0.37) | AXLNUDT1BRD4APP | |
| SCHEMBL18430380 | 0.75 | AXL (0.37) | AXLNUDT1BRD4APPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |