Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167148 | 0.79 | AXL (0.41) | AXLNUDT1BRD4APP | |
| SCHEMBL11888031 | 0.76 | AXL (0.38) | AXLNUDT1BRD4APP | |
| SCHEMBL31283256 | 0.75 | AXL (0.41) | AXLNUDT1BRD4APP | |
| SCHEMBL6929283 | 0.75 | CCR1 (0.50) | AXLNUDT1BRD4APP | |
| SCHEMBL6928507 | 0.75 | CCR1 (0.50) | AXLNUDT1BRD4APP | |
| SCHEMBL10130905 | 0.74 | AXL (0.37) | AXLNUDT1BRD4APP | |
| SCHEMBL18430380 | 0.74 | AXL (0.37) | AXLNUDT1BRD4APP | |
| Hydrochloric Acid SCHEMBL4976930 | 0.73 | AXL (0.39) | AXLNUDT1BRD4APP | |
| SCHEMBL12874655 | 0.73 | KCNH2 (0.43) | AXLNUDT1BRD4APPKCNH2 | |
| SCHEMBL23517237 | 0.71 | AXL (0.39) | AXLNUDT1BRD4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183758-A1 | Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans | CB RESEARCH AND DEVELOPMENT, INC. (US) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183758-A1 | Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans | TPMT, INMT, AANAT | AXL 2823/4885NUDT1 21/4885BRD4 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.