Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928543 | 0.87 | DRD2 (0.43) | DRD2DRD3HTR7HTR1ADRD4 | |
| Oxalic Acid SCHEMBL6926575 | 0.83 | KCNH2 (0.41) | DRD2DRD3HTR7HTR1ADRD4 | |
| SCHEMBL6928645 | 0.80 | PARP1 (0.40) | DRD2HTR6PARP1PPARGPPARA | |
| SCHEMBL6926651 | 0.79 | DRD2 (0.55) | DRD2DRD3HTR7HTR1ADRD4 | |
| SCHEMBL6928842 | 0.78 | DRD2 (0.47) | DRD2DRD3HTR7HTR1AHTR2A | |
| SCHEMBL14761735 | 0.71 | DRD2 (0.57) | DRD2DRD3HTR7HTR1ADRD4 | |
| SCHEMBL6930016 | 0.71 | PARP1 (0.39) | DRD2HTR6PARP1PPARGPPARA | |
| SCHEMBL6929163 | 0.70 | DRD2 (0.52) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL6924603 | 0.70 | DRD3 (0.55) | DRD2DRD3HTR7HTR1AHTR6 | |
| SCHEMBL6928660 | 0.69 | PARP1 (0.38) | DRD2DRD3HTR7HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514993-B1 | Useful in the treatment of certain psychic and neurologic disorders | H. LUNDBECK A/S (DK) | 2003-02-04 | — | — | US | disclosed |
| EP-0770066-B1 | SEROTONIN 5-HT 1A AND DOPAMIN D2 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2000-05-17 | — | — | EP | disclosed |