Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925532 | 0.85 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6926532 | 0.85 | TACR1 (0.66) | TACR1 | |
| SCHEMBL7801183 | 0.82 | TACR1 (0.66) | TACR1 | |
| SCHEMBL6922478 | 0.82 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6926023 | 0.81 | TACR1 (0.69) | TACR1 | |
| SCHEMBL6923703 | 0.79 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6926951 | 0.78 | TSPO (0.59) | TACR1 | |
| SCHEMBL6922317 | 0.77 | PPARG (0.66) | TACR1 | |
| SCHEMBL6928698 | 0.77 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6926601 | 0.76 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518273-B1 | 2-aryl indole derivative as antagonists of tachykinins | MERCK SHARP & DOHME LTD. | 2003-02-11 | — | — | US | disclosed |