Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 17/20 | 0.77 |
| ▸ | MME | P08473 | 15/20 | 0.77 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.72 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697199 | 0.93 | ACE2 (0.70) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL6928069 | 0.92 | ACE2 (0.81) | ECE1MMEACE2 | |
| SCHEMBL6928872 | 0.88 | ACE2 (0.66) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL9715281 | 0.87 | ACE2 (0.62) | ECE1MMEACE2 | |
| SCHEMBL6924974 | 0.87 | ECE1 (1.00) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL6927544 | 0.87 | ECE1 (0.88) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL6924717 | 0.86 | ACE2 (0.84) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL7615297 | 0.86 | ECE1 (0.76) | ECE1MMEACE2 | |
| SCHEMBL6928956 | 0.86 | ECE1 (0.79) | ECE1MMEMMP8MMP14 | |
| SCHEMBL6923553 | 0.86 | ECE1 (0.68) | ECE1MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518260-B1 | (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2003-02-11 | — | — | US | disclosed |