Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.81 |
| ▸ | ECE1 | P42892 | 18/20 | 0.80 |
| ▸ | MME | P08473 | 16/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615297 | 0.94 | ECE1 (0.76) | ACE2ECE1MME | |
| SCHEMBL7619188 | 0.93 | ACE2 (0.72) | ACE2ECE1MME | |
| SCHEMBL6928745 | 0.92 | ECE1 (0.77) | ACE2ECE1MME | |
| SCHEMBL6924717 | 0.90 | ACE2 (0.84) | ACE2ECE1MME | |
| SCHEMBL7621700 | 0.89 | ECE1 (1.00) | ECE1MME | |
| SCHEMBL3865857 | 0.89 | ECE1 (0.68) | ACE2ECE1MME | |
| SCHEMBL6924974 | 0.88 | ECE1 (1.00) | ACE2ECE1MME | |
| SCHEMBL6925939 | 0.87 | ECE1 (0.88) | ECE1MME | |
| SCHEMBL6927544 | 0.86 | ECE1 (0.88) | ACE2ECE1MME | |
| SCHEMBL6923553 | 0.85 | ECE1 (0.68) | ACE2ECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518260-B1 | (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2003-02-11 | — | — | US | disclosed |
| EP-1009750-B1 | NOVEL (ALPHA-AMINOPHOSPHINO) PEPTIDE DERIVATIVES, METHOD FOR MAKING SAME AND THERAPEUTIC APPLICATIONS THEREOF | INST NAT SANTE RECH MED (FR) | 2002-07-31 | — | — | EP | disclosed |