SCHEMBL6928762

SCHEMBL6928762

COc1ccc(N=NC(C(C)=O)C(=O)Nc2ccccc2OC)c([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
RAB9A P51151 5/20 0.48
MAPT P10636 6/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 4/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
ATM Q13315 1/20 0.45
THRB P10828 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
AKR1C3 P42330 2/20 0.44
AKR1C2 P52895 2/20 0.44
KDM4E B2RXH2 1/20 0.42
ABCB1 P08183 1/20 0.42
ABCC1 P33527 1/20 0.42
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352667 1.00 MEN1 (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL12760851 1.00 MEN1 (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL340919 0.90 RAB9A (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL16322841 0.90 RAB9A (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL16322845 0.90 RAB9A (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL29352162 0.90 RAB9A (0.48) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL2141173 0.90 KMT2A (0.49) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL12760841 0.90 KMT2A (0.49) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL12760842 0.90 KMT2A (0.49) MEN1KMT2ARAB9AMAPTSMN1; SMN2
SCHEMBL29354820 0.90 KMT2A (0.49) MEN1KMT2ARAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043008-B2 Method for repairing self-sealing tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-07-23 US claimed
EP-3984728-A1 METHOD FOR REPAIRING SELF-SEALING TIRES AND SEALANT COMPOSITION The Goodyear Tire & Rubber Company (US) 2022-04-20 EP claimed
US-20220111609-A1 METHOD FOR REPAIRING SELF-SEALING TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2022-04-14 US claimed
US-9981065-B2 Dermal filler composition AGHA RANIA (US) 2018-05-29 US claimed
US-20150320907-A1 DERMAL FILLER COMPOSITION AGHA RANIA (US) 2015-11-12 US claimed
US-12521952-B2 Self sealing tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 2026-01-13 US disclosed
US-12420507-B2 Self-sealing pneumatic tire with noise suppression characteristics THE GOODYEAR TIRE & RUBBER COMPANY (US) 2025-09-23 US disclosed
EP-4163094-B1 SELF-SEALING PNEUMATIC TIRE GOODYEAR TIRE & RUBBER (US) 2025-05-14 EP disclosed
WO-2024263606-A1 EXTENDED SKIN COLOR MODULATION COMPOSITIONS AND METHODS TALEI BENJAMIN (US) 2024-12-26 WO disclosed
US-20240326361-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2024-10-03 US disclosed
EP-4438280-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2024-10-02 EP disclosed
CN-118725473-A Sealant composition for self-sealing pneumatic tire 固特异轮胎和橡胶公司 2024-10-01 CN disclosed
US-20150320907-A1 DERMAL FILLER COMPOSITION AGHA RANIA (US) 2015-11-12 US disclosed
WO-2014202216-A1 RESIN IMPREGNATED COATED ARTICLE WITH IMPROVED AESTHETIC PROPERTIES SURFACTOR GERMANY GMBH (DE) 2014-12-24 WO disclosed
CN-103834150-A Material composition for producing beer bottle and production method of bear bottle BEIJING CHAMGO NANO TECH CO LTD 2014-06-04 CN disclosed
US-20120248563-A1 POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PRODUCING POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, POLARIZATION OPTICAL DEVICE, IMAGING DEVICE, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2012-10-04 US disclosed
EP-2506329-A2 Polarization Organic Photoelectric Conversion Device, Method for Producing Polarization Organic Photoelectric Conversion Device, Polarization Optical Device, Imaging Device and Electronic Apparatus Sony Corporation (JP) 2012-10-03 EP disclosed
US-6514595-B1 Dry formulation of hydraulic or cementitious binder, redis-persible polymeric cement modifier, retroreflective filler and optionally reflective filler for fresh or hardened con-crete and asphalt roads MBT HOLDING AG (CH) 2003-02-04 US disclosed
EP-1082274-A1 INTEGRATED RETROREFLECTIVE MARKING MATERIALS MBT HOLDING AG (CH) 2001-03-14 EP disclosed
WO-1999057076-A1 INTEGRATED RETROREFLECTIVE MARKING MATERIALS MBT HOLDING AG (CH) 1999-11-11 WO disclosed