Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928803 | 1.00 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7761920 | 1.00 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7756877 | 0.98 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7756850 | 0.98 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7761662 | 0.98 | SIGMAR1 (0.55) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6927378 | 0.94 | SIGMAR1 (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6923750 | 0.94 | SIGMAR1 (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8421138 | 0.94 | SIGMAR1 (0.63) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7756844 | 0.92 | SIGMAR1 (0.52) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7761653 | 0.92 | SIGMAR1 (0.52) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518309-B1 | Poly-substituted isothiouronium salts as microbiocida surface active antifouling agents | RHOCRAFT RESEARCH AND DEVELOPMENT LTD. (CA) | 2003-02-11 | — | — | US | claimed |
| WO-2001079359-A2 | GUANIDINIUM AND ISOTHIOURONIUM COMPOUNDS AND METHODS FOR THEIR USE | UNIVERSITY OF VICTORIA INNOVATION AND DEVELOPMENT CORPORATION (CA) | 2001-10-25 | — | — | WO | claimed |