Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274482 | 0.79 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL9079943 | 0.76 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL6429482 | 0.76 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL7211598 | 0.74 | CYP2D6 (0.37) | CYP2D6CYP2C19P2RX7 | |
| SCHEMBL7703026 | 0.70 | MAPT (0.37) | CYP2D6CYP2C19P2RX7 | |
| SCHEMBL7211051 | 0.67 | CYP2C19 (0.41) | CYP2D6CYP2C19 | |
| SCHEMBL11703278 | 0.66 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL11703272 | 0.66 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL7211020 | 0.65 | CYP2D6 (0.39) | CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL3021932 | 0.64 | CYP2D6 (0.38) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012208-A4 | CROSS-LINKED PARTICLES | ACCESS PHARMACEUTICALS AUSTRAL (AU) | 2003-06-18 | — | — | EP | disclosed |
| US-6221397-B1 | POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER | BIOTECH AUSTRALIA PTY LIMITED (AU) | 2001-04-24 | — | — | US | disclosed |
| EP-1012208-A1 | CROSS-LINKED PARTICLES | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999011703-A1 | CROSS-LINKED PARTICLES | BIOTECH AUSTRALIA PTY. LIMITED (US) | 1999-03-11 | — | — | WO | disclosed |