SCHEMBL7703026

SCHEMBL7703026

COC(=O)C1(C(=O)O)C[C@H]2C=C[C@@H]1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
SIGMAR1 Q99720 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211598 0.91 CYP2D6 (0.37) MAPTCYP2D6CYP2C19SIGMAR1P2RX7
SCHEMBL6429482 0.84 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL9079943 0.84 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL6325212 0.83 CYP2D6 (0.32) CYP2D6CYP2C19
SCHEMBL27619841 0.83 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL11703278 0.81 CYP2D6 (0.37) MAPTCYP2D6CYP2C19
SCHEMBL11703272 0.81 CYP2D6 (0.37) MAPTCYP2D6CYP2C19
SCHEMBL200115 0.76 P2RX7 (0.41) MAPTCYP2D6CYP2C19P2RX7
SCHEMBL18938394 0.76 P2RX7 (0.41) MAPTCYP2D6CYP2C19P2RX7
SCHEMBL13525792 0.75 CYP2D6 (0.35) CYP2D6CYP2C19P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348296-B1 COPOLYMER CONSISTING OF 2,3-DI-TERT-BUTYL-5-NORBORNENE-2,3-DICARBOXYLATE, ANOTHER NORBORNENE MONOMER, AND MALEIC ANHYDRIDE HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-02-19 US claimed