Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004330 | 0.77 | TDP1 (0.32) | TSHR | |
| SCHEMBL2543351 | 0.76 | TSHR (0.34) | TSHR | |
| SCHEMBL6285016 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL156098 | 0.74 | TDP1 (0.36) | TSHR | |
| SCHEMBL11404332 | 0.72 | TSHR (0.34) | TSHRPGRADRA2AADRA2BHTR2A | |
| SCHEMBL675175 | 0.72 | TDP1 (0.35) | TSHR | |
| SCHEMBL4670578 | 0.71 | PGR (0.41) | TSHRPGRADRA2AADRA2BHTR2A | |
| SCHEMBL2570923 | 0.71 | TSHR (0.34) | TSHR | |
| SCHEMBL17350349 | 0.71 | TDP1 (0.31) | TSHR | |
| SCHEMBL4497966 | 0.71 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639029-B1 | Atom trasfer radical polymerization of acrylate esters using copper metal catalyst; narrow molecular weight distribution; high molecular weight | ROHMAX ADDITIVES GMBH (DE) | 2003-10-28 | — | — | US | disclosed |
| US-6610801-B1 | Acrylates with alkyl chains with at least 8 carbons; narrow molecular weight distribution; high molecular weight; ligands form a coordination compound with copper catalyst; initiator containing a transferable group (halide, sulfonyl halide) | ROHMAX ADDITIVES GMBH (DE) | 2003-08-26 | — | — | US | disclosed |
| US-6610802-B2 | Polymerizing unsatd. monomers with a transition metal catalyst and a coordination compound-forming ligand; filtration using a filter aid having carboxylic acid-, sulfonic acid- or phosphonic acid-containing units | ROHMAX ADDITIVES GMBH (DE) | 2003-08-26 | — | — | US | disclosed |
| US-20030060587-A1 | Process for synthesis of polymer compositions, polymer compositions obtainable by the process, and use of the same | ROHMAX ADDITIVES GMBH (DE) | 2003-03-27 | — | — | US | disclosed |