⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104332 | 0.73 | — | — | |
| SCHEMBL561897 | 0.50 | — | — | |
| SCHEMBL4016818 | 0.39 | — | — | |
| SCHEMBL30900645 | 0.32 | — | — | |
| SCHEMBL1585970 | 0.32 | — | — | |
| SCHEMBL10358941 | 0.28 | — | — | |
| SCHEMBL6559802 | 0.28 | — | — | |
| Methane SCHEMBL17599294 | 0.28 | — | — | |
| SCHEMBL11667125 | 0.28 | — | — | |
| SCHEMBL8152548 | 0.28 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735599-A | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands | BOEHRINGER INGELHEIM PHARMA (US) | 2006-02-15 | — | — | CN | claimed |
| CN-101878026-B | Pharmacological adjunctive therapy associated with glaucoma filtration surgery | BAUSCH & LOMB | 2013-11-20 | — | — | CN | disclosed |
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | disclosed |
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1735599-A | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands | BOEHRINGER INGELHEIM PHARMA (US) | 2006-02-15 | — | — | CN | disclosed |
| US-6514964-B1 | Treating diseases, conditions or disorders mediated by integrin receptors, such as vitronectin and fibronectin receptors | AMGEN INC. | 2003-02-04 | — | — | US | disclosed |