Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.63 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.62 |
| ▸ | OSBP | P22059 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | RORC | P51449 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.52 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.51 |
| ▸ | UGCG | Q16739 | 2/20 | 0.51 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571498 | 1.00 | POLA1 (0.63) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7711483 | 1.00 | POLA1 (0.63) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL17268824 | 1.00 | POLA1 (0.63) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7670481 | 0.91 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7670476 | 0.91 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL19759234 | 0.90 | POLA1 (0.60) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL9305083 | 0.90 | POLA1 (0.65) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL9305078 | 0.90 | POLA1 (0.65) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL21261326 | 0.90 | POLA1 (0.67) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5346090 | 0.90 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030017124-A1 | Two-coat make-up product containing a goniochromatic pigment and monochrome pigment, and make-up kit containing this product | L'OREAL (FR) | 2003-01-23 | — | — | US | claimed |
| EP-0892023-B1 | Opaque pigment flakes | CIBA SC HOLDING AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| US-20030017124-A1 | Two-coat make-up product containing a goniochromatic pigment and monochrome pigment, and make-up kit containing this product | L'OREAL (FR) | 2003-01-23 | — | — | US | disclosed |
| US-6358574-B1 | CROSSLINKED POLYSILOXANES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2002-03-19 | — | — | US | disclosed |
| US-6224664-B1 | MIXTURES CONTAINING PIGMENTS OF ORIENTED THREE-DIMENSIONALLY CROSSLINKED LIQUID CRYSTAL WITH CHIRAL PHASE, BOTH MATCHED IN SUCH A WAY THAT APPLICATION OF THE MIXTURE AT DIFFERENT TEMPERATURES, THERE IS NOT VISUAL COLOR DIFFERENCE OF PAINT | WACKER-CHEMIE GMBH (DE) | 2001-05-01 | — | — | US | disclosed |
| CN-1061079-C | Polymerizable liquid-crvstalline siloxanes | CONSORTIUM ELEKTROCHEM IND (DE) | 2001-01-24 | — | — | CN | disclosed |
| US-6107447-A | LIQUID CRYSTALLINE POLYMERS | HOECHST RESEARCH TECHNOLOGY DEUTCHLAND GMBH & CO. KG (DE) | 2000-08-22 | — | — | US | disclosed |
| US-6071438-A | Process for the production of three-dimensionally crosslinked polymeric materials having broad cholesteric reflection bands, and filters, reflectors and polarizers produced by this process | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2000-06-06 | — | — | US | disclosed |
| US-6040411-A | Low glass temperature organosiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |
| EP-0892023-A1 | Opaque pigment flakes | Ciba SC Holding AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| US-5824733-A | Aqueous coating product and a process for producing multiple layer paint coatings whose perceived color varies with the angle from which they are viewed | WACKER-CHEMIE GMBH (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5788880-A | Liquid-crystalline organosiloxanes containing chiral dianhydrohexitol derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1998-08-04 | — | — | US | disclosed |
| US-5683622-A | Optical elements having color-selective and polarization-selective reflection containing LC pigments, and the production of these elements | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5641850-A | HYDROSILATION OF A HYDRIDOPOLYSILOXANE BY AN ALKENE CONTAINING MESOGENIC GROUPS FOLLOWED BY REACTION WITH AN ALKENE CONTAINING A (METH)ACRYLOXY GROUP; CROSSLINKING; HAZE-FREE FILMS | CONSORTIUM FUR ELECTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5605649-A | LOW VISCOSITY, THERMOCHROMIC PROPERTIES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| CN-1109091-A | Polymerizable liquid-crvstalline siloxanes | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-09-27 | — | — | CN | disclosed |
| US-5442025-A | Organosilsesquioxanes having at least one mesogenic side group | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1995-08-15 | — | — | US | disclosed |
| US-5231206-A | CYCLIC ORGANOSILOXANES HAVING NONLINEAR OPTICAL PROPERTIES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5211877-A | Crosslinked resins | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030017124-A1 | Two-coat make-up product containing a goniochromatic pigment and monochrome pigment, and make-up kit containing this product | KIT, GYPA, TYR | POLA1 921/4885CYP46A1 857/4885OSBP 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.