Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.54 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15372829 | 0.98 | GRM2 (0.52) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL23177172 | 0.93 | LTB4R (0.54) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL16468979 | 0.93 | LTB4R (0.54) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL28556411 | 0.90 | SLC13A5 (0.50) | GRM2GRM3HDAC1HDAC2LMNA | |
| SCHEMBL27748006 | 0.89 | GRM2 (0.51) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL202819 | 0.89 | GRM2 (0.51) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL3616371 | 0.89 | GRM2 (0.51) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| Hydrochloric Acid SCHEMBL31587976 | 0.87 | GRM2 (0.50) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| Hydrochloric Acid SCHEMBL1807415 | 0.87 | GRM2 (0.50) | GRM2GRM3POLBSMN1; SMN2HDAC3 | |
| SCHEMBL584902 | 0.81 | LTB4R (0.59) | GRM2GRM3POLBSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399311-A1 | NOVEL PEPTIDE BASED PCSK9 VACCINE | ZYDUS LIFESCIENCES LIMITED (IN) | 2020-12-24 | — | — | US | claimed |
| EP-3609532-A1 | NOVEL PEPTIDE BASED PCSK9 VACCINE | Cadila Healthcare Limited (IN) | 2020-02-19 | — | — | EP | claimed |
| CN-110536696-A | PCSK9 vaccine based on new peptide | CADILA HEALTHCARE LTD | 2019-12-03 | — | — | CN | claimed |
| WO-2018189705-A1 | NOVEL PEPTIDE BASED PCSK9 VACCINE | CADILA HEALTHCARE LIMITED (IN) | 2018-10-18 | — | — | WO | claimed |
| US-8383581-B2 | Short-chain peptides as parathyroid hormone (PTH) receptor agonist | CADILA HEALTHCARE LIMITED (IN) | 2013-02-26 | — | — | US | claimed |
| WO-2012120532-A2 | CYCLIC SHORT CHAIN PEPTIDES | CADILA HEALTHCARE LIMITED (IN) | 2012-09-13 | — | — | WO | claimed |
| US-20120108496-A1 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2012-05-03 | — | — | US | claimed |
| CN-102405229-A | Short-chain peptides as parathyroid hormone (PTH) receptor agonists | CADILA HEALTHCARE LTD | 2012-04-04 | — | — | CN | claimed |
| EP-2421893-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | Cadila Healthcare Limited (IN) | 2012-02-29 | — | — | EP | claimed |
| WO-2010128521-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-11325945-B2 | Peptide based PCSK9 vaccine | CADILA HEALTHCARE LIMITED (IN) | 2022-05-10 | — | — | US | disclosed |
| US-20200399311-A1 | NOVEL PEPTIDE BASED PCSK9 VACCINE | ZYDUS LIFESCIENCES LIMITED (IN) | 2020-12-24 | — | — | US | disclosed |
| CN-110869544-A | Cyclic peptide compound having high membrane permeability and library containing same | 中外制药株式会社 | 2020-03-06 | — | — | CN | disclosed |
| WO-2010128521-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |
| US-4808713-A | Anthypertensive pyridazo [1,2-a][1,2]diazepines | HOFFMAN-LA ROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4772701-A | Pyridazo[1,2]pyridazines and pyrazolo[1,2]pyridazines as antihypertensives | HOFFMANN-LA ROCHE INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4658024-A | Pyrazolo [1,2-a][1,2]-diazepines useful as antihypertensives | HOFFMANN-LA ROCHE INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4512924-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108496-A1 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | PTH1R, GIPR, PTMS | GRM2 1931/4885GRM3 1460/4885POLB 3831/4885 |
| US-11325945-B2 | Peptide based PCSK9 vaccine | PCSK9, PCSK7, PCSK6 | GRM2 4722/4885GRM3 4238/4885POLB 3143/4885 |
| US-20200399311-A1 | NOVEL PEPTIDE BASED PCSK9 VACCINE | PCSK9, PCSK7, PCSK6 | GRM2 4711/4885GRM3 4280/4885POLB 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.