Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930688 | 0.87 | KMT2A (0.62) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| SCHEMBL6934470 | 0.85 | CHEK1 (0.43) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3499092 | 0.84 | CHEK1 (0.43) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| SCHEMBL17777448 | 0.82 | MAPT (0.50) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19371465 | 0.81 | MAPT (0.49) | KMT2AMEN1POLBALDH1A1NPC1 | |
| Phenyl Biguanide SCHEMBL27966486 | 0.80 | HSD17B10 (0.52) | KMT2AMEN1POLBALDH1A1NPC1 | |
| SCHEMBL7877536 | 0.80 | KMT2A (0.66) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| SCHEMBL4795890 | 0.80 | KMT2A (0.66) | KMT2AMEN1POLBTDP1ALDH1A1 | |
| SCHEMBL1741887 | 0.79 | CYP1A2 (0.59) | KMT2AMEN1POLBALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL28340523 | 0.78 | CYP1A2 (0.57) | KMT2AMEN1POLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865434-B1 | COMPOUNDS AND THEIR USE TO TREAT INFECTIOUS DISEASES | PICOWER INST MED RES (US) | 2003-12-17 | — | — | EP | claimed |