Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895690 | 0.87 | MEN1 (0.63) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL6930252 | 0.87 | KMT2A (0.55) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL2546537 | 0.86 | MEN1 (0.61) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1185244 | 0.86 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4795890 | 0.85 | KMT2A (0.66) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL7877536 | 0.85 | KMT2A (0.66) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL7975430 | 0.85 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29568124 | 0.84 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.84 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9323576 | 0.83 | L3MBTL1 (0.54) | KMT2AMEN1TDP1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865434-B1 | COMPOUNDS AND THEIR USE TO TREAT INFECTIOUS DISEASES | PICOWER INST MED RES (US) | 2003-12-17 | — | — | EP | claimed |
| EP-3981780-A1 | ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF | Arrowhead Pharmaceuticals, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3535397-B1 | ALPHA-V BETA-6 INTEGRIN LIGANDS AND USES THEREOF | ARROWHEAD PHARMACEUTICALS INC (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-0865434-B1 | COMPOUNDS AND THEIR USE TO TREAT INFECTIOUS DISEASES | PICOWER INST MED RES (US) | 2003-12-17 | — | — | EP | disclosed |
| US-5376685-A | Arylhydrazones using as SAMDC inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5238941-A | S-adenosylmethionine decarboxylase inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0335832-B1 | ARYL HYDRAZONES | CIBA-GEIGY AG (CH) | 1993-02-10 | — | — | EP | disclosed |
| US-5118709-A | Decarboxylase enzyme inhibitors; antitumor agents | CIBA-GEIGY CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971986-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0335832-A2 | Aryl hydrazones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |