Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 5/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ELOC | Q15369 | 3/20 | 0.32 |
| ▸ | ELOB | Q15370 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930341 | 1.00 | ATM (0.43) | ATMVHLACEMMEMEN1 | |
| SCHEMBL4440457 | 0.80 | ATM (0.39) | ATMACEMME | |
| SCHEMBL4440451 | 0.80 | ATM (0.39) | ATMACEMME | |
| SCHEMBL15125848 | 0.78 | VHL (0.49) | VHLELOCELOB | |
| SCHEMBL12798577 | 0.72 | ACE (0.55) | ATMACEPOLB | |
| SCHEMBL29720853 | 0.72 | NAALAD2 (0.37) | VHLACE | |
| SCHEMBL6933806 | 0.69 | ATM (0.61) | ATMVHLACEMMEMEN1 | |
| SCHEMBL6933807 | 0.69 | ATM (0.61) | ATMVHLACEMMEMEN1 | |
| SCHEMBL1991504 | 0.69 | ATM (0.61) | ATMVHLACEMMEMEN1 | |
| SCHEMBL8444112 | 0.68 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009420-B1 | CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER | MERCK & CO INC (US) | 2003-12-17 | — | — | EP | disclosed |