Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 8/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440451 | 1.00 | ATM (0.39) | ATMDPP4DPP8DPP9ACE | |
| SCHEMBL5734357 | 0.81 | DPP4 (0.44) | DPP4DPP8DPP9ACE | |
| SCHEMBL4595209 | 0.81 | DPP4 (0.44) | DPP4DPP8DPP9ACE | |
| SCHEMBL4595206 | 0.81 | DPP4 (0.44) | DPP4DPP8DPP9ACE | |
| SCHEMBL6930338 | 0.80 | ATM (0.43) | ATMACEMME | |
| SCHEMBL6930341 | 0.80 | ATM (0.43) | ATMACEMME | |
| SCHEMBL5036645 | 0.78 | TACR1 (0.40) | DPP4DPP8DPP9 | |
| SCHEMBL10454953 | 0.77 | TRHR (0.43) | DPP4DPP8DPP9ACE | |
| SCHEMBL7759091 | 0.77 | DPP4 (0.42) | DPP4DPP8DPP9ACE | |
| SCHEMBL10454951 | 0.77 | TRHR (0.43) | DPP4DPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |