SCHEMBL6930378

SCHEMBL6930378

C=CC=CC(=CC=CC(=O)O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
RECQL P46063 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28298539 0.84 LMNA (0.30) LMNA
SCHEMBL18389724 0.84 LMNA (0.30) LMNA
SCHEMBL24022689 0.82 LMNA (0.41) TSHRALDH1A1ALOX15RECQLHSD17B10
SCHEMBL7061506 0.82 LMNA (0.41) TSHRALDH1A1ALOX15RECQLHSD17B10
SCHEMBL51021 0.81
SCHEMBL51020 0.81
SCHEMBL418689 0.81
SCHEMBL15541082 0.78
SCHEMBL23116541 0.78
Hydrochloric Acid SCHEMBL11508580 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605404-B2 Coated Carriers XEROX CORPORATION 2003-08-12 US claimed
US-20030064314-A1 Coated carriers XEROX CORPORATION 2003-04-03 US claimed
US-5928830-A Latex processes XEROX CORPORATION (US) 1999-07-27 US claimed
US-6605404-B2 Coated Carriers XEROX CORPORATION 2003-08-12 US disclosed
US-20030064314-A1 Coated carriers XEROX CORPORATION 2003-04-03 US disclosed
US-5928830-A Latex processes XEROX CORPORATION (US) 1999-07-27 US disclosed