Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830398 | 0.89 | MEN1 (0.47) | MAPTPOLBKDM1AMEN1KMT2A | |
| SCHEMBL5832045 | 0.86 | CYP19A1 (0.46) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL5831040 | 0.83 | KMT2A (0.43) | ALDH1A1KDM1AMEN1KMT2AFSCN1 | |
| SCHEMBL5831396 | 0.80 | MEN1 (0.50) | MAPTPOLBKDM1AMEN1KMT2A | |
| SCHEMBL5831931 | 0.80 | PFKFB3 (0.46) | MAPTALDH1A1KDM1ARAB9AMEN1 | |
| SCHEMBL5831701 | 0.75 | FSCN1 (0.44) | MAPTPOLBALDH1A1KDM1AMEN1 | |
| SCHEMBL5831683 | 0.75 | ADORA3 (0.52) | POLBKDM1ARAB9AMEN1KMT2A | |
| SCHEMBL5831167 | 0.74 | KDM1A (0.47) | MAPTPOLBALDH1A1KDM1ARAB9A | |
| SCHEMBL2762529 | 0.74 | KDM1A (0.57) | MAPTPOLBKDM1AMEN1KMT2A | |
| SCHEMBL5831263 | 0.72 | FSCN1 (0.47) | ALDH1A1KDM1AMEN1KMT2AFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113310-A1 | USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |