SCHEMBL6930535

SCHEMBL6930535

CC(=O)OC(C)[C@H](Br)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
CYP2C19 P33261 1/20 0.46
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ALDH1A1 P00352 3/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
GALR3 O60755 1/20 0.34
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.32
ALOX15 P16050 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6930533 1.00 TSHR (0.46) TSHRCYP2C19CHRM2CHRM4CHRM1
SCHEMBL9628038 0.79 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL11121400 0.79 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL26634370 0.77
SCHEMBL28825680 0.77
SCHEMBL26764604 0.77
SCHEMBL10239103 0.76 TSHR (0.65) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL9720211 0.76 TSHR (0.65) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL17751390 0.76 TSHR (0.65) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL9656098 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149068-A4 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER SAMSUNG FINE CHEMICALS CO LTD (KR) 2003-01-02 EP disclosed
EP-1149068-A1 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER Samsung Fine Chemicals Co., Ltd. (KR) 2001-10-31 EP disclosed
WO-2000046186-A1 A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER SAMSUNG FINE CHEMICALS CO., LTD (KR) 2000-08-10 WO disclosed