Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930533 | 0.79 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6930535 | 0.79 | TSHR (0.46) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL11121400 | 0.77 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL5718201 | 0.76 | — | — | |
| SCHEMBL26764604 | 0.75 | — | — | |
| SCHEMBL28825680 | 0.75 | — | — | |
| SCHEMBL26634370 | 0.75 | — | — | |
| SCHEMBL9720211 | 0.74 | TSHR (0.65) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10239103 | 0.74 | TSHR (0.65) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL17751390 | 0.74 | TSHR (0.65) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238252-B1 | PREPARATION OF AZETIDINONES AND INTERMEDIATES | SCHERING CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5089609-A | 4-benzoyl azetidinones | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-5008404-A | Preparation of azetidinones via novel protected intermediates | SCHERING CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4963670-A | Preparation of azetidinones via novel protected intermediates | SCHERING CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4882429-A | Stereospecific preparation of (3S,4R,5R)-3-(1-hydroxyethyl)-4-benzoyloxy-azeridinones from L-(-)-theonine | SCHERING CORPORATION (US) | 1989-11-21 | — | — | US | disclosed |
| US-4827006-A | Preparation of azetidinones via novel protected intermediates | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4740595-A | Preparation of azetidinones via N-protected oxirancecarboxamide intermediates | SCHERING CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0238252-A2 | Preparation of azetidinones and intermediates | SCHERING CORPORATION (US) | 1987-09-23 | — | — | EP | disclosed |