Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12134731 | 0.83 | BCHE (0.47) | BCHEACHEPDE10AALDH1A1KMT2A | |
| SCHEMBL23502659 | 0.77 | BCHE (0.43) | BCHEACHEPDE10AALDH1A1KMT2A | |
| SCHEMBL2646721 | 0.76 | PDE10A (0.69) | PDE10AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL14075106 | 0.75 | BCHE (0.38) | BCHEACHEPDE10AALDH1A1KMT2A | |
| SCHEMBL1597577 | 0.75 | BCHE (0.46) | BCHEACHEALDH1A1KDM4EMAPK14 | |
| Hydrochloric Acid SCHEMBL11604764 | 0.73 | BCHE (0.45) | BCHEACHEALDH1A1KDM4EMAPK14 | |
| SCHEMBL7514147 | 0.73 | ALDH1A1 (0.47) | PDE10AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL22479749 | 0.71 | BCHE (0.46) | BCHEACHEPDE10AALDH1A1MAPT | |
| SCHEMBL1104821 | 0.71 | BCHE (0.54) | BCHEACHEALDH1A1KDM4EMAPK14 | |
| SCHEMBL2928822 | 0.71 | BCHE (0.46) | BCHEACHEALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |