SCHEMBL6930692

SCHEMBL6930692

O=C1NN(c2ccccc2)CC1(O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
G6PD P11413 3/20 0.51
GAA P10253 3/20 0.51
MAPT P10636 2/20 0.51
ALDH1A1 P00352 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALOX5 P09917 8/20 0.47
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975058 0.82 G6PD (0.56) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL5693724 0.80 G6PD (0.50) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL271530 0.78 G6PD (0.55) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL3135479 0.77 G6PD (0.51) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL271985 0.75 G6PD (0.67) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL5177925 0.74 G6PD (0.51) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL8372106 0.74 G6PD (0.51) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL8743852 0.73 G6PD (0.50) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL8372107 0.73 G6PD (0.64) G6PDGAAMAPTALDH1A1SMN1; SMN2
SCHEMBL9007793 0.73 G6PD (0.50) G6PDGAAMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903342-B1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics OREAL (FR) 2003-12-17 EP claimed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US claimed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US disclosed
US-5004670-A Containing hydrazide, dihydroxybenzene developers, sulfite, and tertiary amine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-04-02 US disclosed