SCHEMBL6930704

SCHEMBL6930704

CCN(C)C(=O)C(c1nsc(NS(=O)(=O)c2c(Cl)cc(Cl)cc2Cl)n1)c1c(Cl)cc(Cl)c(S(=O)(=O)Nc2nc(CC(=O)N3CCSCC3)ns2)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6930698 0.86 HSD11B1 (0.47) HSD11B1
SCHEMBL5831094 0.83 HSD11B1 (0.56) HSD11B1
SCHEMBL5831698 0.79 HSD11B1 (0.49) HSD11B1
SCHEMBL5831436 0.75 HSD11B1 (0.56) HSD11B1
SCHEMBL5831702 0.74 HSD11B1 (0.41) HSD11B1
SCHEMBL5830689 0.73 HSD11B1 (0.71) HSD11B1
SCHEMBL5830658 0.71 HSD11B1 (0.50) HSD11B1
SCHEMBL5830857 0.70 HSD11B1 (0.62) HSD11B1
SCHEMBL5830977 0.69 HSD11B1 (0.44) HSD11B1
SCHEMBL5831130 0.69 HSD11B1 (0.37) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004113310-A1 USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING BIOVITRUM AB (SE) 2004-12-29 WO disclosed