SCHEMBL693114

SCHEMBL693114

N[C@@H](CC(=O)OC(=O)CC[C@H](N)C(=O)OC(=O)C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 8/20 0.44
GRIK2 Q13002 6/20 0.44
SLC1A1 P43005 3/20 0.44
GRM1 Q13255 2/20 0.44
GRM2 Q14416 2/20 0.44
GRIA4 P48058 2/20 0.44
GRIK3 Q13003 2/20 0.44
GRIK5 Q16478 2/20 0.44
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
GSR P00390 2/20 0.44
GRM8 O00222 1/20 0.44
GRM6 O15303 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CYP1A2 P05177 1/20 0.44
GRM5 P41594 1/20 0.44
GRIA1 P42261 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA3 P42263 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817851 1.00 GRIK1 (0.44) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL27574890 0.98 SLC1A1 (0.42) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL17184332 0.93 SLC1A1 (0.46) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL1410127 0.93 SLC1A1 (0.48) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL16054489 0.91 ALOX15 (0.43) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL7717181 0.91 SLC1A1 (0.54) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL931954 0.91 SLC1A1 (0.54) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL2994699 0.91 SLC1A1 (0.54) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL6267781 0.91 SLC1A1 (0.54) GRIK1GRIK2SLC1A1GRM1GRM2
SCHEMBL3430330 0.91 SLC1A1 (0.54) GRIK1GRIK2SLC1A1GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353357-B2 Polypeptides having phytase activity and the encoding nucleic acids AB ENZYMES GMBH (DE) 2016-05-31 US claimed
EP-2773674-A1 IMMUNOLOGIC CONSTRUCTS AND METHODS Vaxinnate Corporation (US) 2014-09-10 EP claimed
US-20140242249-A1 POLYPEPTIDE HAVING PHYTASE ACTIVITY AND INCREASED TEMPERATURE RESISTANCE OF THE ENZYME ACTIVITY, AND NUCLEOTIDE SEQUENCE CODING SAID POLYPEPTIDE AB ENZYMES GMBH (DE) 2014-08-28 US claimed
US-20140235836-A1 Immunologic Constructs and Methods VAXINNATE CORPORATION (US) 2014-08-21 US claimed
WO-2013066365-A1 IMMUNOLOGIC CONSTRUCTS AND METHODS VAXINNATE CORPORATION (US) 2013-05-10 WO claimed
EP-2102334-B1 POLYPEPTIDE HAVING PHYTASE ACTIVITY AND INCREASED TEMPERATURE RESISTANCE OF THE ENZYME ACTIVITY, AND NUCLEOTIDE SEQUENCE CODING SAID POLYPEPTIDE AB ENZYMES GMBH (DE) 2013-04-03 EP claimed
US-20110262619-A1 POLYPEPTIDE HAVING PHYTASE ACTIVITY AND INCREASED TEMPERATURE RESISTANCE OF THE ENZYME ACTIVITY, AND NUCLEOTIDE SEQUENCE CODING SAID POLYPEPTIDE AB ENZYMES GMBH (DE) 2011-10-27 US claimed
CN-101305810-A Polypeptide calcium and application SHAOTONG LI (CN) 2008-11-19 CN claimed
US-5739273-A CONJUGATED BACTERIORHODOPSIN FOR DRUG DELIVERY YALE UNIVERSITY (US) 1998-04-14 US claimed
EP-0564561-A4 PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS GEORGIA TECH RES INST (US) 1994-08-10 EP claimed
EP-0564561-A1 PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS GEORGIA TECH RESEARCH CORPORATION (US) 1993-10-13 EP claimed
WO-1992012140-A1 PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS GEORGIA TECH RESEARCH CORPORATION (US) 1992-07-23 WO claimed
US-4488989-A ESTERS, DETERGENTS, STORAGE STABILITY LEVER BROTHERS COMPANY (US) 1984-12-18 US claimed
JP-8217751-A None JP disclosed
US-20240016724-A1 SLURRY DISPERSION, COSMETIC AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-18 US disclosed
EP-4245377-A1 SLURRY DISPERSION, COSMETIC AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-20 EP disclosed
EP-0483261-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1992-05-06 EP disclosed
WO-1991001328-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1991-02-07 WO disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed
CN-1038649-A By extracting and the purifying anticoagulant composition in the leech of South America MERRELL DOW PHARMA (US) 1990-01-10 CN disclosed