Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934798 | 0.88 | TDP1 (0.46) | KMT2AMEN1MAPTL3MBTL1TSHR | |
| SCHEMBL6935779 | 0.86 | PTK2 (0.41) | KMT2AMEN1MAPTHTTPOLB | |
| SCHEMBL14596620 | 0.84 | KMT2A (0.51) | KMT2AMEN1HSD17B10NAPRTMAPT | |
| SCHEMBL6936521 | 0.83 | GAA (0.46) | KMT2AMEN1MAPTGAAPOLB | |
| SCHEMBL6933157 | 0.73 | GAA (0.46) | KMT2AMEN1HSD17B10MAPTL3MBTL1 | |
| Diethylamine SCHEMBL9400390 | 0.73 | KMT2A (0.41) | KMT2AMEN1HSD17B10NAPRTMAPT | |
| SCHEMBL6930354 | 0.73 | POLB (0.46) | KMT2AMEN1MAPTL3MBTL1TSHR | |
| SCHEMBL6934812 | 0.73 | KIF11 (0.31) | KMT2AMEN1HSD17B10L3MBTL1POLB | |
| SCHEMBL9400382 | 0.71 | MEN1 (0.45) | KMT2AMEN1MAPTL3MBTL1TSHR | |
| SCHEMBL6932807 | 0.71 | SMN1; SMN2 (0.42) | KMT2AMEN1MAPTL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | claimed |
| JP-11152271-A | — | — | None | — | — | JP | disclosed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| JP-H11152271-A | NEW 4,4-DIHYDROXY-5-PYRAZOLINONE COMPOUND, ITS PREPARATION AND ITS USE TO COSMETIC | L'OREAL SA | 1999-06-08 | — | — | JP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |