Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.37 |
| ▸ | MMP2 | P08253 | 8/20 | 0.37 |
| ▸ | MMP9 | P14780 | 8/20 | 0.37 |
| ▸ | MMP8 | P22894 | 8/20 | 0.37 |
| ▸ | MMP13 | P45452 | 8/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744930 | 0.83 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL4652884 | 0.76 | MMP1 (0.39) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL4651561 | 0.74 | MMP1 (0.38) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL10506021 | 0.73 | MMP1 (0.43) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6259411 | 0.72 | MMP1 (0.46) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2744932 | 0.72 | F2 (0.31) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL5026615 | 0.71 | MMP1 (0.34) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL4650782 | 0.71 | MMP1 (0.34) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7920243 | 0.71 | TSHR (0.38) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL5024952 | 0.71 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |