Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210263 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL7767347 | 0.67 | KMT2A (0.45) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL1253347 | 0.65 | NPC1 (0.43) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL6931329 | 0.63 | — | — | |
| SCHEMBL11727183 | 0.59 | GAA (0.40) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL11908592 | 0.59 | KDM4E (0.53) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL6930202 | 0.59 | — | — | |
| SCHEMBL9203100 | 0.58 | NPC1 (0.46) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL6376132 | 0.58 | NPC1 (0.50) | ALDH1A1KDM4ENPSR1NPC1KMT2A | |
| SCHEMBL7875824 | 0.58 | ADORA2B (0.44) | ALDH1A1KDM4ENPSR1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |