Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL1833350 | 1.00 | ALDH1A1 (0.67) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL30999729 | 0.90 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL29039922 | 0.90 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL28966847 | 0.90 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL30122831 | 0.90 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL8162329 | 0.90 | ALDH1A1 (0.74) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL1532704 | 0.87 | ALDH1A1 (0.78) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL30182240 | 0.87 | ALDH1A1 (0.78) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL3671128 | 0.87 | ALDH1A1 (0.78) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 | |
| Phthalic Acid SCHEMBL5888909 | 0.87 | ALDH1A1 (0.78) | ALDH1A1ALOX15AKR1C3KDM4EHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440991-A | Polysiloxane composition | 默克专利有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-109180048-B | Nano precursor medium transmission inhibitor and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-109180048-A | A kind of nanometer of presoma medium transport inhibitors and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2019-01-11 | — | — | CN | disclosed |
| US-6525908-B1 | Floppy disk | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| US-4253886-A | Corrosion resistant ferromagnetic metal powders and method of preparing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |